Carsten schmuck. Arginine mimetic appended peptide

Welcome to the Supramolecular Chemistry Group

carsten schmuck

The certificate was signed by the Nobel Laureates Ben Feringa and Sir Fraser Stoddart who held inspiring lectures at the symposium. . How important is molecular rigidity for the complex stability of artificial host-guest systems? Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins. Carsten Schmuck Der Tod von Prof. He invented so many things that we still use today, even though in a modified and improved version, but still essentially going back to his ideas. Clicking on the donut icon will load a page at altmetric.

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Book Review: Highlights in Bioorganic Chemistry

carsten schmuck

Design and synthesis of a new class of arginine analogues with an improved anion binding site in the side chain Chemical Communications. Dimensional control of supramolecular assemblies of diacetylene-derived peptide gemini amphiphile: from spherical micelles to foamlike networks. Inspired by natural metallopeptides, chemists have developed artificial peptides which coordinate with metal ions through their functional groups either for introducing a special reactivity or for constructing nanostructures. And I guess by now my coworkers are much more skilled in the lab than I am due to lack of practice. Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks.

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Welcome to the Supramolecular Chemistry Group

carsten schmuck

If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc. The supramolecular self-assembly of 1 can be controlled by three stimuli, namely light, pH, and addition of metal ions, in both organic and aqueous media. Formation of Polymer Particles by Direct Polymerization on the Surface of a Supramolecular Template. Unexpected stable dimerisation of an anionic imidopyrrolecarboxylate in polar solution. Later in school I had a very good chemistry teacher who encouraged me to take part in the International Chemistry Olympiad an international competition for high school kids. This review briefly discusses strategies of peptide self-assembly induced by metal coordination to different natural and non-natural binding sites in the peptide.

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Carsten Schmuck

carsten schmuck

Incorporation of arginine mimetic residue into peptides for recognition of double stranded nucleic acid structure: Binding and aggregation studies. Several modes of supramolecular assembly relying on noncovalent as well as dynamic covalent interactions were combined in a single molecule. The multi-stimuli-responsive nature of 1 was used successfully for the controlled encapsulation and on-demand release of hydrophobic molecules, such as dyes and drugs. It was a five-step synthesis of one of the building blocks, a guanidiniocarbonyl pyrrole derivative, we need for our research. We are fascinated by supramolecular chemistry.

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Multi

carsten schmuck

Citations are the number of other articles citing this article, calculated by Crossref and updated daily. A tailor-made specific anion-binding motif in the side chain transforms a tetrapeptide into an efficient vector for gene delivery. So I guess if chemistry or natural sciences were not my profession I would have ended up in medicine. A molecular peptide beacon for the ratiometric sensing of nucleic acids. None I could find on using a book as a tool for survival instead of as a manual for survival.

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Arginine mimetic appended peptide

carsten schmuck

What made you want to be a chemist? A fluorescent light-up probe as an inhibitor of intracellular β-tryptase. A readily accessible survey for everyone wishing to stay abreast of developments. We strive to understand how molecules interact with each other, how non-covalent interactions control the stability and selectivity of molecular interactions and how we can use this understanding to develop supamolecular systems that either bind to biological targets such as proteins or nucleic acids or self-assemble with themselves to form supramolecular polymers and gels. Two-Component Self-Assembly: Hierarchical Formation of pH-Switchable Supramolecular Networks by pi-pi Induced Aggregation of Ion Pairs. Rational Design, Binding Studies and Crystal Structure Evaluation of the First Ligand Targeting the Dimerization Interface of the 14-3-3ζ Adapter Protein. The American Chemical Society holds a copyright ownership interest in any copyrightable Supporting Information.

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Carsten Schmuck

carsten schmuck

Recently, this protein family has been identified as a relevant therapeutic target involved in many human diseases. I got ambitious and the more I got involved with chemistry, the more I loved it. Is there a book, how to make coffee from coconuts? We also highlight some examples of a metal-induced peptide self-assembly with relevance to biotechnology applications. We can make new molecules, that never existed before; new molecules with new and much desired properties. A supramolecular gel from a quadruple zwitterion that responds to both acid and base.

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Carsten Schmuck (1968

carsten schmuck

It was about six years ago when I just started my own academic career and when I had only three coworkers who just started to work with me for their diploma. Chemistry Weinheim An Der Bergstrasse, Germany. Unfortunately, I do not have any time for lab research myself any more. And on that day I also present some experiments like the classical nylon synthesis or gun cotton. Editorial Review The book offers an interesting overview of current research topics of working groups from the universities in Europe, which are dealing with bioorganic chemistry.

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